EZ Cat 2 can now loads its database from anywhere. By default it looks for its database in the same place as the program executable but this can be changed in the options screen. If you want to temorarily load in a different database you can use the "Load..." option under the "Database" menu. To reload the default database use the "Load default" option on the "Database" menu.
A database is stored as a directory with a collection of .t .i and .f files in it. So, when you load a new database EZ Cat prompts you for a folder. To make a new database, just make a new folder somewhere with Windows Explorer.